I said the first is a stimulant effect, and over and above that the patient goes into a state of somnolence and, yes. That is, I mean, the patient becomes drowsy and if it exceeds that point, the patient loses consciousness and when the dose is further increased the patient goes into a coma and, subsequently, if it's further increased the patient dies. That - let's put it that way. It depends - it's all dose related and also it depends on the tolerance of the patient. There are certain patients who will, you know, depending on their exposure to the drug have developed tolerance to the drug and, you know, they have to be given higher levels of the drug to achieve a particular state of mind and things like that.